Uneven Skin Tone & Discolouration

As your skin ages and is exposed to UVA & UVB rays, the rate at which new skin cells develop slows down. As a result, the balance of new skin cells versus old is changed. Additionally, collagen and elastin begin to break down causing the skin to loose resilience.

Causes of Uneven Skin Tone

As skin ages, it develops visible signs of this ageing process; most commonly fine line, wrinkles, sagging and discolouration. Exposure of the skin to environmental stresses is inevitable, as are the associated signs.

Treatment for Uneven Skin Tone

The Obagi Nu-Derm System is the number 1 physician dispensed prescription strength skin care system. It works by penetrating the surface of the skin to transform the function of the skin cells at a cellular level, correcting the damage from within.

Related Products

OBAGI360 System
- Dull, dry and uneven skin tone
- Minimal fine lines and wrinkles
- Occasional breakouts or loss of radiance
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Topilase
Topilase^® is an innovative alternative to injectable hyaluronidase created by an aesthetic doctor that provides a non-invasive, topical response to excess hyaluronic acid.

What is Topilase^®?
From SoftFil cosmetics, Topilase^® is the first patent-pending topical treatment option for adjusting the skin’s hyaluronic acid level. The first-of-its-kind, this non-injectable skincare product is composed of 100% natural ingredients capable of smoothing out irregularities. In addition, it can reduce the voluminous appearance following an injection, and adjust the level of hyaluronic acid present in the skin, even reabsorbing excess product.
Topilase^® was created by an aesthetic doctor to avoid potential inconveniences some patients experience with injectable hyaluronidase, such as skin laxity, significant and long-lasting dehydration, and even allergic reactions triggered by ingredients of animal origin. There are no reported side effects of Topilase^®. The patent-pending formula is based on an enzymatic complex of lipase, protease, and hyaluronidase, in addition to natural ingredients known for their soothing and repairing effects: aloe vera, lavender, hydrangea, myrrh and cistus. The ideal formulation to effectively reduce unsightly surface volumes.
Left: Before applying Topilase^® Right: After 3 sessions of Topilase^®.
How Topilase^® works
1. Reduces the appearance of swelling to restore the skin’s natural appearance
2. Models and unifies the surface of the skin.
3. Smooths surface irregularities and reduces the appearance of defects associated with the presence of injected hyaluronic acid
How to use Topilase^® works
A layer of the solution is applied to the area and massaged into the skin. Within minutes, signs of an over-filled feature will start to reduce. You may need between one and four sessions of Topilase® to minimise the volume.

Watch a video of how to use Topilase®
Watch a video of this patient’s Topilase® testimony
Topilase^® seen in:
Harper’s Bazaar: Coming Soon: Topilase, a Cream That Can Fine-Tune Your Filler Results (December 2022)
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The Skin Care Management System™
The Jan Marini Skin Research Skin Care Management System™ has won “The Best Skin Care System” for 13 years running in NewBeauty Magazine’s Annual Beauty Choice Awards.
This all-inclusive, five-step hydration skincare set includes a range of essential products, from cleanser to sunscreen, to promote healthy and youthful skin. By harnessing key technologies that collaborate seamlessly, it offers optimal outcomes for various skin issues. The holistic approach of this comprehensive regimen combines the power of Vitamin C, peptides, growth factors, AHA and BHA exfoliators, hydrating agents, and sunscreen. Together, they work swiftly to enhance the look of uneven skin tone, texture irregularities, and sun-induced damage, delivering noticeable improvements in a short period.
Choose from dry to very dry skin, and normal or combination skin, in full-size or starter kits.
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Obagi Nu-Derm Fx System
- Anti aging and Correction
- Moderate-to-severe hyperpigmentation (inc Melasma)
- Fine lines & wrinkles, laxity & rough uneven texture
- Adult Acne
- Oily or greasy skin
- Enhancement of procedure results
  *Trial Kits available, treatment duration approx. 6 weeks. Please note Obagi Hydrate is not included and should be purchased separately.
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Blue Peel RADIANCE
- Fine lines, wrinkles & light melasma
- Pigmentary changes due to acne in darker skin
- Uneven skin tone, laxity & texture issues
- Boost outcome of other systems such as Nu-Derm, Obagi-C Rx & CLENZIderm
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Sunscreens
Jan Marini Skin Research provides three heavy-weight SPF options to suit people of all skin tones, skin types and lifestyles. All products provide broad-spectrum UVA and UVB protection to decrease the risk of premature skin ageing. Choose from tinted and untinted formulas, as well as SPF 45 or 30. Green tea extract, alpha-bisabolol and co-enzyme Q10 help to improve overall skin quality, soothe the skin and provide added antioxidant protection against free radical damage caused by the sun and environmental stresses. Choose from Marini Physical Protectant SPF 45 (Tinted), Marini Physical Protectant SPF 30 (Untinted) and Antioxidant Daily Face Protectant SPF 33.
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Injectables
Healthxchange stocks a wide range of injectable sundries;
- Bacteriostatic
- Sodium chloride
- Durolane
- Hyalase
- Topilase
- Potassium chloride
- Water for injections
We also carry a range of other aesthetic sundries as well as cannulas, needles and sutures.

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The Skincare Makeup System
The foundation of great skin. Give your clients everything they want (and deserve) from makeup in one high-performance system. Nourishing. Natural-looking. Lasting. Just three easy steps.
- Step 1: Prep with SmoothAffair Primer for a smooth canvas and lasting results.Ultra-hydrating Smooth Affair Face Primer blurs imperfections, evens skin texture and holds makeup fast. This creates a smooth canvas for easy foundation application and a smudge-proof finish for longer wear. Choose from 3 primers to suit your clients’ skin type.
- Step 2: Perfect with PurePressed Base Mineral Foundation SPF 20/15 to get flawless coverage and a skin-like feel. Multitasking PurePressed Base Mineral Foundation conceals, protects and nourishes with weightless, line-blurring coverage. The natural, semi-matte finish looks and feels like skin and allows skin to breathe and function optimally. 26 true-to-you shades offered.
- Step 3: Set with Hydration Spray - the secret weapon for all-day wear. Botanical-infused Pommisst Hydration Spray adds moisture and acts as a liquid binder. This helps promote foundation adhesion for enhanced transfer-resistance and a flawless, more skin-like appearance. Choose from 4 Hydration Sprays to cater for your clients’ skin concern.
Achieve powerful skincare benefits. Our high-performance makeup is more than meets the eye. Each formula contains nuturing ingredients that support the health of the skin.
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Masks and peels
Jan Marini Skin Research’s progressive glycolic resurfacing peels and masks address multiple skin concerns with virtually no downtime or recovery period. Suitable for all skin types, Jan Marini Skin Research masks can significantly improve the appearance and quality of the skin.
Healthxchange customers can get exclusive access to the Jan Marini Physicians Kit 70% Peel.
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Concealers
Clean, effective post-treatment camouflage solutions for a more comfortable recovery.
- Disappear™ Full Coverage Concealer. A matte, opaque concealer. Recommended for: Oily/Acneic Skin and clients that want extra coverage
- Corrective Colors. Four shades to correct and conceal discoloration. Recommended for: Post-procedure.
- Circle\Delete® Concealer. Double sided color corrector and highlighter. Recommend for: someone who need concealing and hydration under their eyes.
- Active Light® Under-Eye Concealer. Soft-focus concealer and brightener. Recommended for: Concealing and reduces the appearance of puffiness.
- Enlighten Concealer™. Corrective concealer. Recommended for: very dark under-eye circles, hyperpigmentation or bruising.
- Enlighten Plus™ Under-Eye Concealer. Full coverage concealer with SPF 20-30. Recommended for: Comprehensive concealing with added skincare benefits and SPF.
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Vitamin C and antioxidants
Antioxidants, most notably Vitamin C, play a vital role in protecting the skin from free radical damage that is known to cause premature aging. Vitamin C antioxidants play a heavy role in the body, such as assisting collagen and elastin production, giving skin its youthful bounce and fullness. Despite the important role it plays in the body, Vitamin C is not naturally produced by humans so it needs to come from external sources, like antioxidant skin care products.
Jan Marini Vitamin C and antioxidant products feature a lipid-soluble form of Vitamin C that has been shown to enhance absorption, retention and efficacy, while its non-acidic formula is ideal for all skin types. In an independent published study in the Journal of Drugs and Dermatology, Jan Marini’s Vitamin C product was shown to be superior to a leading traditional Vitamin C product in a blinded head-to-head consumer study showing superior results, satisfaction and value.
Explore the range, such as Rejuvenate & Protect, C-ESTA® Face Cream and Serum and more.
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Cleansers
Jan Marini Skin Research cleansers are gentle yet hard-working formulas, that remove makeup and impurities without irritation.
Choose from the popular:
Bioglycolic® Face Cleanser
Bioglycolic® Face Cleanser’s non-foaming, hydrating cleanser leaves the skin clean, soft and hydrated and eliminates the need for harsh post-cleansing toners or astringents. Glycolic acid provides deep follicular cleansing to remove impurities and dead cells from the skin and preps the skin for enhanced benefits from additional products used as part of a skincare program.
C-ESTA® Cleansing Gel
C-ESTA Cleansing Gel, containing Vitamin C and DMAE, is a potent skin conditioning cleanser with a luxurious lather. This vitamin C face cleanser is suitable for all skin types.
Clean Zyme®
Proteolytic enzymes derived from green unripened papaya (papain) gently resurface to reveal healthy, smooth and polished skin. Clean Zyme® cleanser is a supplemental home care exfoliation product that has the ability to selectively remove dead skin cells without harming sensitive or irritated tissues.
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Rosacea treatment
Jan Marini Skin Research’s acclaimed systems and products can provide dramatic results against rosacea and unwanted redness.
RosaLieve® Experience relief from unwanted facial redness with the Jan Marini RosaLieve Redness Reducing Complex. This cream contains azelaic acid and natural extracts including oat, green tea, white tea, red tea and boswellia serrata, which work together to help reduce the appearance of redness and visible flushing. In addition, the Skin Care Management System works to target multiple key concerns, including redness.
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Exfoliators and retinols
Jan Marini Skin Research’s exfoliating and retinol skincare products improve the appearance of texture, sun damage other concerns. Choose from fan-favourite products such as the Bioglycolic® Resurfacing Body Scrub, Age Intervention® Retinol Plus, Jan Marini Juveneck, Skin Zyme® Mask, Luminate® Face Mask, Hyla3D™ Face Serum and more.
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Hyaluronic acids and moisturisers
Jan Marini’s award-winning range of hyaluronic acids and moisturisers hydrate the skin, reduce the appearance of fine lines and improve the appearance of texture and overall skin tone. Browse the Hyla3D™ Face Serum and Face Cream , Jan Marini Regeneration Booster, Transformation Face Cream, Juveneck and more.
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